How sure can we be to have identified the right proteins in a large scale proteomics study with our mass spectrometric instrumentation? Can we expect valid data from the employed search algorithm(s)? Can we believe what our computer is telling us? Right questions—what are the answers?
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Elias, J.E., Haas, W., Faherty, B.K. & Gygi, S.P. Nat. Methods 2, 667–675 (2005).
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Chamrad, D., Meyer, H. Valid data from large-scale proteomics studies. Nat Methods 2, 647–648 (2005). https://doi.org/10.1038/nmeth0905-647
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DOI: https://doi.org/10.1038/nmeth0905-647
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