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Next-gen immunohistochemistry

An Erratum to this article was published on 27 June 2014

This article has been updated

The combination of mass spectroscopy with immunohistochemistry allows highly multiplexed, directly quantitative imaging of tissue samples for both basic and clinical research.

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  • 23 May 2014

    In the version of this article initially published, the surname of the first author of ref. 1 was misspelled as "Geisen"; the correct spelling is "Giesen." The error has been corrected in the HTML and PDF versions of the article.

References

  1. Giesen, C. et al. Nat. Methods 11, 417–422 (2014).

    Article  CAS  Google Scholar 

  2. Angelo, M. et al. Nat. Med. doi:10.1038/nm.3488 (2 March 2014).

  3. Shi, S.R., Cote, R.J. & Taylor, C.R. Appl. Immunohistochem. Mol. Morphol. 9, 107–116 (2001).

    CAS  PubMed  Google Scholar 

  4. Camp, R.L., Chung, G.G. & Rimm, D.L. Nat. Med. 8, 1323–1327 (2002).

    Article  CAS  Google Scholar 

  5. Gerdes, M.J. et al. Proc. Natl. Acad. Sci. USA 110, 11982–11987 (2013).

    Article  CAS  Google Scholar 

  6. Bendall, S.C. et al. Science 332, 687–696 (2011).

    Article  CAS  Google Scholar 

  7. Bordeaux, J. et al. Biotechniques 48, 197–209 (2010).

    Article  CAS  Google Scholar 

  8. Robb, J.A. et al. Arch. Pathol. Lab. Med. doi:10.5858/arpa.2013-0250-CP (12 August 2013).

  9. Begley, C.G. & Ellis, L.M. Nature 483, 531–533 (2012).

    Article  CAS  Google Scholar 

  10. Neumeister, V.M. et al. Lab. Invest. doi:10.1038/labinvest.2014.7 (17 February 2014).

Download references

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Correspondence to David L Rimm.

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D.L.R. is a scientific cofounder and stockholder in Metamark Genetics, Inc.

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Rimm, D. Next-gen immunohistochemistry. Nat Methods 11, 381–383 (2014). https://doi.org/10.1038/nmeth.2896

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