Although it has been thought that female mammals develop all the eggs they will ever have by the time they are born, new research suggesting otherwise has now sparked a debate.
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References
Johnson, J., Canning, J., Kaneko, T., Pru, J.K. & Tilly, J.L. Nature 428, 145–150 (2004).
Zuckerman, S. Recent Prog. Horm. Res. 6, 63–108 (1951).
Johnson, J. et al. Cell 122, 303–315 (2005).
Lee, H.J. et al. J. Clin. Oncol. 25, 3198–3204 (2007).
Baker, T.G. Proc. R. Soc. Lond. B 158, 417–433 (1963).
Gougeon, A. & Chainy, G.B. J. Reprod. Fertil. 81, 433–442 (1987).
Byskov, A.G., Faddy, M.J., Lemmen, J.G. & Andersen, C.Y. Differentiation 73, 438–446 (2005).
Telfer, E.E. et al. Cell 122, 821–822 (2005).
Johnson, J. et al. Cell Cycle 4, 1471–1477 (2005).
Eggan, K., Jurga, S., Gosden, R., Min, I.M. & Wagers, A.J. Nature 441, 1109–1114 (2006).
Begum, S., Papaioannou, V.E. & Gosden, R.G. Hum. Reprod. 23, 2326–2330 (2008).
Bristol-Gould, S.K. et al. Dev. Biol. 298, 132–148 (2006).
Bristol-Gould, S.K. et al. Dev. Biol. 298, 149–154 (2006).
Faddy, M. & Gosden, R. Cell Cycle 6, 1951–1952 (2007).
Daggag, H. et al. Biol. Reprod. 79, 468–474 (2008).
Anderson, E.L. et al. Proc. Natl. Acad. Sci. USA 105, 14976–14980 (2008).
Tilgner, K. et al. Stem Cells published online, doi:10.1634/stemcells.2008-0289 (18 September 2008).
Hubner, K. et al. Science 300, 1251–1256 (2003).
Woodruff, T.K. Cancer Treat. Res. 138, 3–11 (2007).
Agarwal, S.K. & Chang, R.J. Cancer Treat. Res. 138, 15–27 (2007).
Gosden, R.G. Reprod. Biomed. Online 4 Suppl 1, 64–67 (2002).
Silber, S.J. et al. Hum. Reprod. 23, 1531–1537 (2008).
Xu, M., Kreeger, P.K., Shea, L.D. & Woodruff, T.K. Tissue Eng. 12, 2739–2746 (2006).
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Woodruff, T. Making eggs: is it now or later?. Nat Med 14, 1190–1191 (2008). https://doi.org/10.1038/nm1108-1190
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DOI: https://doi.org/10.1038/nm1108-1190
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