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A renaissance for the tumor immunosurveillance hypothesis

Nature Medicine volume 7, pages 1178–1180 (2001)Cite this article

Little was known about the function of T cells expressing the γδ–T-cell receptor, until these cells were shown to protect against skin cancer. But what is the mechanism mediating this activity?

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Figure 1: Over-expression of NKG2D ligands by transformed cells facilitates recognition by the immune system.

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  1. Department of Microbiology and Immunology and the Cancer Research Institute University of California, San Francisco, San Francisco, California, USA

    Lewis L. Lanier

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  1. Lewis L. Lanier
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Lanier, L. A renaissance for the tumor immunosurveillance hypothesis. Nat Med 7, 1178–1180 (2001). https://doi.org/10.1038/nm1101-1178

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