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HIV's great escape

Nature Medicine volume 9, pages 1262–1263 (2003)Cite this article

Viruses need cellular proteins to help them escape from cells. New results show that HIV and other viruses use the cellular machinery that normally delivers proteins to late endosomes and lysosomes.

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Figure 1: HIV assembly occurs either at the plasma membrane or on late endosomes.

Kimberly Homer

References

  1. Freed, E.O. Trends Microbiol. 11, 56–59 (2003).

    Article  CAS  Google Scholar 

  2. Pornillos, O., Garrus, J.E. & Sundquist, W.I. Trends Cell Biol. 12, 569–579 (2002).

    Article  CAS  Google Scholar 

  3. von Schwedler, U. et al. Cell 114, 701–713 (2003).

    Article  CAS  Google Scholar 

  4. Strack, B. et al. Cell 114, 689–699 (2003).

    Article  CAS  Google Scholar 

  5. Hui, E.K.-W., Barman, S., Yang, T.Y. & Nayak, D.P. J. Virol. 77, 7078–7092 (2003).

    Article  CAS  Google Scholar 

  6. Katzmann, D.J., Odorizzi, G. & Emr, S.D. Nat. Rev. Mol. Cell. Biol. 3, 893–905 (2002).

    Article  CAS  Google Scholar 

  7. Stoorvogel, W., Kleijmeer, M.J., Geuze, H.J. & Raposo, G. Traffic 3, 321–330 (2002).

    Article  CAS  Google Scholar 

  8. Swanstrom, R. & Wills, J.W. in Retroviruses (eds. Coffin, J.M., Hughes, S.H. & Varmus, H.E.) 263–334 (Cold Spring Harbor Laboratory Press, New York, 1997).

    Google Scholar 

  9. Gottlinger, H.G., Dorfman, T., Sodroski, J.G. & Haseltine, W.A. Proc. Natl. Acad. Sci. USA 88, 3195–3199 (1991).

    Article  CAS  Google Scholar 

  10. Martin-Serrano, J., Zang, T. & Bieniasz, P.D. Nat. Med. 7, 1313–1319 (2001).

    Article  CAS  Google Scholar 

  11. Odorizzi, G., Katzmann, D.J., Babst, M., Audhya, A. & Emr, S.D. J. Cell. Sci. 116, 1893–1903 (2003).

    Article  CAS  Google Scholar 

  12. Blott, E.J. & Griffiths, G.M. Nat. Rev. Mol. Cell. Biol. 3, 122–131 (2002).

    Article  CAS  Google Scholar 

  13. Reddy, A., Caler, E.V. & Andrews, N.W. Cell 106, 157–169 (2001).

    Article  CAS  Google Scholar 

  14. Pelchen-Matthews, A., Kramer, B. & Marsh, M. J. Cell Biol. 162, 443–455 (2003).

    Article  CAS  Google Scholar 

  15. Gould, S.J., Booth, A.M. & Hildreth, J.E. Proc. Natl. Acad. Sci. USA; published online 28 August 2003 (doi: 10.1073/pnas.1831413100).

Download references

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Authors and Affiliations

  1. MRC Laboratory for Molecular Cell Biology and Dept of Biochemistry, University College London, Gower Street, London, WC1E 6BT, UK

    Mark Marsh & Markus Thali

  2. Department of Microbiology and Molecular Genetics, University of Vermont, 318 Stafford Hall, 95 Carrigan Drive, Burlington, 05405-0084, Vermont, USA

    Mark Marsh & Markus Thali

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  1. Mark Marsh
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Marsh, M., Thali, M. HIV's great escape. Nat Med 9, 1262–1263 (2003). https://doi.org/10.1038/nm1003-1262

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