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Oxidized lipid protects against sepsis

Nature Medicine volume 8, pages 1084–1085 (2002)Cite this article

Treatment with an oxidized phospholipid markedly reduces tissue damage in a mouse model of sepsis. But will the approach be feasible in humans?

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Figure 1: An oxidized phospholipid (oxPAPC) inhibits LPS-induced expression of adhesion molecules in endothelial cells.

Kimberly Homer

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  1. Department of Pathology, University of Michigan Medical School, Ann Arbor, Michigan, USA

    Niels C. Riedemann & Peter A. Ward

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  1. Niels C. Riedemann
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  2. Peter A. Ward
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Riedemann, N., Ward, P. Oxidized lipid protects against sepsis. Nat Med 8, 1084–1085 (2002). https://doi.org/10.1038/nm1002-1084

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