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News and Views
Nature Medicine  9, 994 - 996 (2003)
doi:10.1038/nm0803-994

Seizing hold of seizures

Gregory L Holmes1 & Yezekiel Ben-Ari2

1  Gregory L. Holmes is in the Section of Neurology, Neuroscience Center at Dartmouth, Dartmouth Medical School, Lebanon, New-Hampshire 03756, USA

2  Yezekiel Ben-Ari is at INMED/ INSERM U29, 163 Route de Luminy, 13273 Marseille, cedex 09, France gregory.l.holmes@dartmouth.edu

Epilepsy remains a hard-to-treat disorder for millions of patients. Gene therapy to target brain regions with seizure-reducing compounds is one approach that has met with limited experimental success. An innovative form of genetic manipulation now reduces seizure susceptibility and seizure-induced brain injury in rats (pages 1076−1080).

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REFERENCE
Epilepsy: Management
Nature Encyclopaedia of Life Sciences
Benzodiazepines
Nature Encyclopaedia of Life Sciences
Epilepsy
Nature Encyclopaedia of Life Sciences

RESEARCH
Tiagabine Synergistically Interacts with Gabapentin in the Electroconvulsive Threshold Test in Mice
Neuropsychopharmacology Original Article (01 Oct 2003)

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