Findings over the last year or so have built the case that microRNAs might contribute to cancer. Three studies now definitively show this to be the case and also suggest that these small RNAs could be used to categorize tumors.
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References
He, L. et al. Nature 435, 828–833 (2005).
O'Donnell K.A. et al. Nature 435, 839–843 (2005).
Lu, J. et al. Nature 435, 834–838 (2005).
Bartel, D.P. Cell 116, 281–297 (2004).
He, L. et al. Nat. Rev. Genet. 5, 522–531 (2004).
Ambros, V. Nature 431, 350–355 (2004).
Lee, R.C. et al. Cell 75, 843–854 (1993).
Reinhart, B.J. et al. Nature 403, 901–906 (2000).
Berezikov, E. et al. Cell 120, 21–24 (2005).
Lewis, B.P. et al. Cell 120, 15–20 (2005).
Krek, A. et al. Nat. Genet. 37, 495–500 (2005).
Calin, G.A. et al. Proc. Natl. Acad. Sci. USA 99, 15524–15529 (2002).
Michael, M.Z. et al. Mol. Cancer Res. 1, 882–891 (2003).
Johnson, S.M. et al. Cell 120, 635–647 (2005).
Dimova, D.K. et al. Oncogene 24, 2810–2826 (2005).
Meltzer, P.S. Nature 435, 745–746 (2005).
Weinberg, R.A. Cell 85, 457–459 (1996).
Weinholds, E. et al. Science published online 26 May 2005 (10.1126/science.1114519).
Iwai, N. et al. Biochem. Biophys. Res. Commun. 331, 1439–1444 (2005).
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Caldas, C., Brenton, J. Sizing up miRNAs as cancer genes. Nat Med 11, 712–714 (2005). https://doi.org/10.1038/nm0705-712
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DOI: https://doi.org/10.1038/nm0705-712
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