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Nature Medicine  9, 820 - 822 (2003)
doi:10.1038/nm0703-820

Dengue immune response: low affinity, high febrility

Raymond M Welsh & Alan L Rothman

The authors are in the Departments of Pathology and Medicine, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA. Raymond.Welsh@umassmed.edu

Immunity built up after dengue virus infection protects only poorly against reinfection by a virus of a different serotype, and second infections are often even more severe. A new study examines why (pages 921−927).

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REFERENCE
Flavivirus Infections in Humans
Nature Encyclopaedia of Life Sciences

REVIEWS
No one is naive: the significance of heterologous t-cell immunity
Nature Reviews Immunology Review Article (01 Jun 2002)

RESEARCH
Original antigenic sin and apoptosis in the pathogenesis of dengue hemorrhagic fever
Nature Medicine Article (01 Jul 2003)

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Nature Medicine
ISSN: 1078-8956
EISSN: 1546-170X
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