Retinaldehyde, an intermediate metabolite between vitamin A and retinoic acid, is present at biologically active concentrations in fat tissue, where it antagonizes PPAR-γ activity, inhibiting adipogenesis and improving insulin sensitivity.
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Kim Caesar
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Desvergne, B. Retinaldehyde: more than meets the eye. Nat Med 13, 671–673 (2007). https://doi.org/10.1038/nm0607-671
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DOI: https://doi.org/10.1038/nm0607-671
