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Selecting the right patient for tumor therapy

Nature Medicine volume 10, pages 577–578 (2004)Cite this article

Two clinical studies have identified mutations affecting the EGF receptor in lung cancers from patients who respond robustly to gefitinib, a small-molecule inhibitor of the receptor tyrosine kinase. This work highlights the importance of conducting clinical trials with an eye to delivering molecule-targeted therapeutics to those patients most likely to benefit.

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Figure 1: Selecting for tumor shinkage.

Kimberly Caesar

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  1. Departments of Medicine and Cancer Biology and Breast Cancer Program, Vanderbilt-Ingram Comprehensive Cancer Center and Vanderbilt University School of Medicine, Nashville, Tennessee, USA

    Carlos L Arteaga

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  1. Carlos L Arteaga
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Arteaga, C. Selecting the right patient for tumor therapy. Nat Med 10, 577–578 (2004). https://doi.org/10.1038/nm0604-577

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