Duane J. Gubler is at the Asia-Pacific Institute of Tropical Medicine and Infectious Diseases, John A. Burns School of Medicine, University of Hawaii at Manoa, Leahi Hospital, 3675 Kilauea Avenue, Honolulu, Hawaii 96816, USA. djg2@cdc.gov
Major countrywide and regional epidemics of dengue and dengue hemorrhagic fever occur in Southeast Asia every three to five years. A model examining the spread of epidemic dengue in Thailand helps explain why such patterns occur.
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