Like every metazoan species hosting a gut flora, drosophila tolerate commensal microbiota yet remain able to mount an efficient immune response to food-borne pathogens. New findings explain how the quantity of reactive oxygen species in the gut is 'tuned' to microbial burden and how intestinal immune homeostasis is thereby maintained.
This is a preview of subscription content, access via your institution
Relevant articles
Open Access articles citing this article.
-
Musashi expression in intestinal stem cells attenuates radiation-induced decline in intestinal permeability and survival in Drosophila
Scientific Reports Open Access 05 November 2020
-
Effects of transient high temperature treatment on the intestinal flora of the silkworm Bombyx mori
Scientific Reports Open Access 13 June 2017
-
Differential modulation of the cellular and humoral immune responses in Drosophila is mediated by the endosomal ARF1-Asrij axis
Scientific Reports Open Access 08 March 2017
Access options
Subscribe to this journal
Receive 12 print issues and online access
$209.00 per year
only $17.42 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Ley, R.E., Peterson, D.A. & Gordon, J.I. Cell 124, 837–848 (2006).
Ha, E.-M. et al. Nat. Immunol. 10, 949–957 (2009).
Lemaitre, B. & Hoffmann, J. Annu. Rev. Immunol. 25, 697–743 (2007).
Ryu, J.H. et al. Science 319, 777–782 (2008).
Maillet, F., Bischoff, V., Vignal, C., Hoffmann, J. & Royet, J. Cell Host Microbe 3, 293–303 (2008).
Lhocine, N. et al. Cell Host Microbe 4, 147–158 (2008).
Zaidman-Remy, A. et al. Immunity 24, 463–473 (2006).
Bischoff, V. et al. PLoS Pathog. 2, e14 (2006).
Ha, E.M., Oh, C.T., Bae, Y.S. & Lee, W.J. Science 310, 847–850 (2005).
Ha, E.M. et al. Dev. Cell 16, 386–397 (2009).
Koropatnick, T.A. et al. Science 306, 1186–1188 (2004).
Ren, M., Feng, H., Fu, Y., Land, M. & Rubin, C.S. Immunity 30, 521–532 (2009).
Ziegler, K. et al. Cell Host Microbe 5, 341–352 (2009).
Powell, J.R., Kim, D.H. & Ausubel, F.M. Proc. Natl. Acad. Sci. USA 106, 2782–2787 (2009).
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Leulier, F., Royet, J. Maintaining immune homeostasis in fly gut. Nat Immunol 10, 936–938 (2009). https://doi.org/10.1038/ni0909-936
Issue Date:
DOI: https://doi.org/10.1038/ni0909-936
This article is cited by
-
Musashi expression in intestinal stem cells attenuates radiation-induced decline in intestinal permeability and survival in Drosophila
Scientific Reports (2020)
-
Differential modulation of the cellular and humoral immune responses in Drosophila is mediated by the endosomal ARF1-Asrij axis
Scientific Reports (2017)
-
Effects of transient high temperature treatment on the intestinal flora of the silkworm Bombyx mori
Scientific Reports (2017)
-
Intestinal FoxO signaling is required to survive oral infection in Drosophila
Mucosal Immunology (2016)
-
Rhodnius prolixus interaction with Trypanosoma rangeli: modulation of the immune system and microbiota population
Parasites & Vectors (2015)
