News and Views
Nature Immunology 8, 909 - 910 (2007)
doi:10.1038/ni0907-909
Holding antigen where B cells can find it
Ian MacLennan1
- Ian MacLennan is with the Medical Research Council Centre for Immune Regulation, The Institute of Biomedical Research, University of Birmingham, Birmingham B15 2TT, UK. e-mail: i.c.m.maclennan@bham.ac.uk
Abstract
Specialized macrophage-like cells initiate antibody responses by trapping antigen in lymph. These antigen-trapping cells are located in the migration pathway of recirculating B cells, which can engage the trapped antigen.
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