Notch1 has an indispensable role in T cell development and NOTCH1 acts as a potent oncogene in T cell leukemia. New data now reveal the role of RNA-binding proteins in regulating the stability of Notch1 mRNA and the induction of T cell leukemia.
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Katie Vicari
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Nedjic, J., Aifantis, I. RNA-binding proteins come out of the shadows. Nat Immunol 11, 697–698 (2010). https://doi.org/10.1038/ni0810-697
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DOI: https://doi.org/10.1038/ni0810-697
