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DNA deaminases converge on adaptive immunity

Nature Immunology volume 8, pages 551–553 (2007)Cite this article

AID acts to further refine the immunoglobulin response in fish, birds and mammals. Now, evidence is uncovered to suggest AID actually arose early in evolution and can diversify antigen receptors in lampreys.

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Figure 1: Assembly and diversification of genes encoding antigen receptors in vertebrates.

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  1. Department of Immunobiology, David G. Schatz is with the Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, Connecticut 06520, USA. david.schatz@yale.edu,

    David G Schatz

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  1. David G Schatz
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Schatz, D. DNA deaminases converge on adaptive immunity. Nat Immunol 8, 551–553 (2007). https://doi.org/10.1038/ni0607-551

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