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Nature Genetics  36, 1034 - 1036 (2004)
doi:10.1038/ng1004-1034

How to make an ape brain

Ajit Varki

Ajit Varki is at the Glycobiology Research and Training Center, Departments of Medicine and Cellular & Molecular Medicine, University of California San Diego, La Jolla, California 92093-0687, USA. a1varki@ucsd.edu

Many genes and genetic mechanisms contributed to the evolution of humans from a common primate ancestor. Emergence of the ape brain was apparently facilitated by a retrotransposed gene duplicate that acquired brain-specific expression and functions affecting the neurotransmitter glutamate.

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Nature Genetics
ISSN: 1061-4036
EISSN: 1546-1718
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