There is a Corrigendum (September 2004) associated with this News and Views.
TGF signaling in health and disease
Rosemary J Akhurst
Rosemary J. Akhurst is at the Mt. Zion Cancer Research Institute, University of California, San Francisco, USA. rakhurst@cc.ucsf.edu
Inactivating mutations in TGFBR2, encoding the transforming growth factor- (TGF) type 2 receptor, may account for up to 10% of cases of Marfan syndrome. This finding has implications for a wider spectrum of disorders, including cancer, fibrosis and inflammatory and cardiovascular diseases, which are influenced by TGF.
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signaling in health and disease
(TGF
