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Nature Genetics 40, 820 - 821 (2008)
doi:10.1038/ng0708-820

Bringing age-related macular degeneration into focus

Rando Allikmets1 & Michael Dean2

  1. Rando Allikmets is at the Departments of Ophthalmology and Pathology and Cell Biology, Columbia University, New York, New York 10032, USA.
    e-mail: rla22@columbia.edu
  2. Michael Dean is at the Laboratory of Experimental Immunology, Cancer and Inflammation Program, National Cancer Institute, Frederick, Maryland 21702, USA.


Genetic studies of age-related macular degeneration (AMD), the most prevalent blinding condition among the elderly, have had both great success and deep controversy. A new study now begins to resolve contradictory views over two candidate genes at a major AMD locus on chromosome 10q26 by suggesting a functional variant in one of these genes.

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