Until very recently, it was widely touted that the complete DNA sequences of any two human beings were 99.9% identical. A new study refutes this notion through a comprehensive comparison of two individual genomes which detects hundreds of new structural genomic variants.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 12 print issues and online access
$209.00 per year
only $17.42 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Iafrate, A.J. et al. Nat. Genet. 36, 949–951 (2004).
Sebat, J. et al. Science 305, 525–528 (2004).
Tuzun, E. et al. Nat. Genet. 37, 727–732 (2005).
Bailey, J.A. et al. Science 297, 1003–1007 (2002).
Cheung, J. et al. Genome Biol. 4, R25 (2003).
van Ommen, G.-J. B. Nat. Genet. 37, 333–334 (2005).
Morley, M. et al. Nature 430, 743–747 (2004).
Stefansson, H. et al. Nat. Genet. 37, 129–137 (2005).
Osborne, L.R. et al. Nat. Genet. 29, 321–325 (2001).
Gonzalez, E. et al. Science 307, 1434–1440 (2005).
Fredman, D. et al. Nat. Genet. 36, 861–866 (2004).
de la Chapelle, A. et al. Am. J. Hum. Genet. 26, 746–765 (1974).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Lee, C. Vive la difference!. Nat Genet 37, 660–661 (2005). https://doi.org/10.1038/ng0705-660
Issue Date:
DOI: https://doi.org/10.1038/ng0705-660
This article is cited by
-
Sexes, species, and genomes: why males and females are not like humans and chimpanzees
Biology & Philosophy (2010)
-
Implications of copy-number variation in the human genome: a time for questions
Nature Reviews Genetics (2006)
-
Decompartmentalizing target validation—thinking outside the pipeline boxes
Journal of Molecular Medicine (2006)
