Department of Radiation and Stress Cell Biology, University of Groningen, Groningen, The Netherlands. o.c.m.sibon@med.rug.nl
Centrosome abnormalities are linked to genomic instability and are considered one possible cause of cancer. A recent study shows that 'abnormal' inactive centrosomes thought to be deleterious to cells actually provide an accurate backup mechanism to the G2/M checkpoint, allowing specific elimination of nuclei with damaged DNA.
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