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News and Views
Nature Genetics  37, 340 - 341 (2005)
doi:10.1038/ng0405-340

Defining stroke risks in sickle cell anemia

James F Meschia1 & V Shane Pankratz2

1  James F. Meschia is in the Department of Neurology, Mayo Clinic, Cannaday Building, 2 East, Jacksonville, Florida 32224, USA. Meschia.james@mayo.edu

2  V. Shane Pankratz is in the Division of Biostatistics, Mayo Clinic, Rochester, Minnesota, 55905 USA.

Children and young adults with sickle cell anemia at risk for stroke are identified principally by screening for cerebral vasculopathy using transcranial Doppler ultrasonography. Investigators now show how Bayesian networks can generate useful predictive models and highlight relationships between genes and the occurrence of stroke in those with sickle cell anemia.

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RESEARCH

Genetic dissection and prognostic modeling of overt stroke in sickle cell anemia

Nature Genetics Letter (01 Apr 2005)

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