Ghia Euskirchen and Michael Snyder are in the Department of Molecular, Cellular and Developmental Biology, Yale University, New Haven, Connecticut. michael.snyder@yale.edu
Understanding how gene expression is regulated on a global scale is important for determining how basic processes such as cell proliferation, cell differentiation and responses to environmental signals are controlled. Three papers now show that it is possible to identify binding sites for key transcription factors in human cells on a chromosome level.
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