Nature Genetics 38, 273 - 274 (2006)
doi:10.1038/ng0306-273
Upending the hair follicleBruce A Morgan
Bruce A. Morgan is in the Cuteneous Biology Research Center, Massachusetts General Hospital, Charlestown, Massachusetts 02129, USA. bruce.morgan@cbrc2.mgh.harvard.edu
A new study profiles microRNA (miRNA) expression in mouse epidermis and hair follicles and examines the requirement for these miRNAs during normal embryonic development. In the absence of Dicer-dependent miRNA production, hair follicles evaginate rather than invaginate, revealing an unexpected role for miRNAs in regulating hair follicle morphogenesis.
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