A new study profiles microRNA (miRNA) expression in mouse epidermis and hair follicles and examines the requirement for these miRNAs during normal embryonic development. In the absence of Dicer-dependent miRNA production, hair follicles evaginate rather than invaginate, revealing an unexpected role for miRNAs in regulating hair follicle morphogenesis.
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Morgan, B. Upending the hair follicle. Nat Genet 38, 273–274 (2006). https://doi.org/10.1038/ng0306-273
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DOI: https://doi.org/10.1038/ng0306-273