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News and Views
Nature Genetics  30, 241 - 242 (2002)
doi:10.1038/ng0302-241

Unraveling heterochromatin

Scott D. Briggs1 & Brian D. Strahl2

1  Department of Biochemistry and Molecular Genetics, University of Virginia Health System, Charlottesville, Virginia, USA.

2  Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA. brian_strahl@med.unc.edu

Using immunological and cytological approaches, researchers are beginning to reveal the complex molecular components of transcriptionally inert, pericentric heterochromatin. A new study shows that histone modifications and a non-Xist RNA component have essential structural roles in maintaining the tight organization of this type of chromatin.

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RESEARCH
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