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Nature Genetics 39, 145 - 146 (2007)
doi:10.1038/ng0207-145
Micromanaging the response to Hedgehog
Philip Ingham1
- Philip Ingham is at the Centre for Developmental and Biomedical Genetics, University of Sheffield, UK, and the Institute of Molecular and Cell Biology, Singapore. e-mail: P.W.Ingham@sheffield.ac.uk
Abstract
Members of the Hedgehog family of secreted proteins are central to animal development, with different levels of Hedgehog signaling activity specifying distinct cellular identities. A new study shows that a microRNA is involved in this process by modulating a component of the Hedgehog signal transduction pathway.
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