Nature Genetics 38, 135 - 136 (2006)
doi:10.1038/ng0206-135
Ciliary proteins and exencephalyNicholas Katsanis
Nicholas Katsanis is at the McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA. katsanis@jhmi.edu
Neural tube defects (NTDs) represent a broad and complex class of brain malformations, and despite much progress in understanding their etiology, many facets of neural tube development and closure remain obscure. Two new studies report the identification of the first two genes responsible for Meckel-Gruber syndrome, one of the major contributors to syndromic NTDs, and implicate defective cilia in its pathogenesis.
REFERENCES
-
Kyttälä, M.
et al. Nat. Genet. 38, 155–157 (2006). | Article |
-
Smith, U.M.
et al. Nat. Genet. 38, 191–196 (2006). | Article |
-
Nauta, J.
et al. J. Am. Doc. Nephrol. 11, 2272–2284 (2000). | ChemPort |
-
Gattone, V.H.
et al. Anat. Rec. A. Discov. Mol. Cell Evol. Biol. 277, 384–395 (2004). | PubMed |
-
Li, J.B.
et al. Cell 117, 541–552 (2004). | Article | PubMed | ISI | ChemPort |
-
Blacque, O.E.
et al. Curr. Biol. 15, 935–941 (2005). | Article | PubMed | ISI | ChemPort |
-
Swoboda, P.
,
Adler, H.T.
&
Thomas, J.H.
Mol. Cell 5, 411–421 (2000). | Article | PubMed | ISI | ChemPort |
-
Ansley, S.J.
et al. Nature 425, 628–633 (2003). | Article | PubMed | ISI | ChemPort |
-
Hildebrandt, F.
&
Otto, E.
Nat. Rev. Genet. 6, 928–940 (2005). | Article | PubMed | ISI | ChemPort |
-
Karmous-Benailly, H.
et al. Am. J. Hum. Genet. 76, 493–504 (2005). | Article | PubMed | ISI | ChemPort |
-
Simons, M.
et al. Nat. Genet. 37, 537–543 (2005). | Article | PubMed | ISI | ChemPort |
-
Torban, E.
,
Kor, C.
&
Gros, P.
Trends Genet. 20, 570–577 (2004). | Article | PubMed | ISI | ChemPort |
-
Ross, A.J.
et al. Nat. Genet. 37, 1135–1140 (2005). | Article | PubMed | ISI | ChemPort |
-
Haycraft, C.J.
et al. PLoS Genet. 1, e53 (2005). | Article | PubMed | ChemPort |
-
Huangfu, D.
et al. Nature 426, 83–87 (2003). | Article | PubMed | ISI | ChemPort |
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