Henry Gee reports on efforts to understand why alcoholics who drink to excess are more resistant to the effects.
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References
Thiele, T.E., Willis, B., Stadler, J., Reynolds, J.G., Bernstein, I.L. & McKnight, G.S. High ethanol consumption and low sensitivity to ethanol-induced sedation in Protein-Kinase-A-mutant mice. Journal of Neuroscience 20, RC75 1 - 6.
Thiele, T.E. et al. Ethanol consumption and resistance are inversely related to Neuropeptide Y levels. Nature 396 366 - 369 1998.
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Gee, H. Sobering thoughts. Nature (2000). https://doi.org/10.1038/news000525-1
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DOI: https://doi.org/10.1038/news000525-1