Review

Nature Clinical Practice Nephrology
Published online: 15 July 2008 | doi:10.1038/ncpneph0880  
Received 30 March 2008 | Accepted 4 June 2008

How should women with pre-eclampsia be followed up? New insights from mechanistic studies

Alexandre Hertig*, Suzanne Watnick, Helena Strevens, Henri Boulanger, Nadia Berkane and Eric Rondeau

Correspondence *Urgences Néphrologiques et Transplantation Rénale, Hôpital Tenon, 4 rue de la Chine, 75020 Paris, France

Email
 alexandre.hertig@tnn.aphp.fr

Considerable progress has been made over the past few years in understanding the pathogenesis of pre-eclampsia. In particular, the contribution of the circulating antiangiogenic factors soluble fms-like tyrosine kinase 1 and endoglin to the vascular and glomerular dysfunction of pre-eclampsia has been recognized. Inspired by these findings, Alexandre Hertig and colleagues from France, the US and Switzerland propose an updated and standardized protocol for the post-delivery follow-up of women with pregnancy-induced hypertension or pre-eclampsia.

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