Review

Nature Clinical Practice Cardiovascular Medicine (2005) 2, 346-351
doi:10.1038/ncpcardio0239  
Received 10 January 2005 | Accepted 6 April 2005

Management of long QT syndrome

Peter J Schwartz

Correspondence Department of Cardiology, IRCCS Policlinico San Matteo, Viale Golgi 19, 27100 Pavia, Italy

Email
 pjqt@compuserve.com

Patients with long QT syndrome can experience life-threatening arrhythmias and related mortality is high among symptomatic, untreated people. Identification of several responsible genes and their effects on ion channels has advanced understanding of this disorder. Here, Peter Schwartz reviews how these discoveries have, or have not, modified management and changed the direction of research.

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