Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Interrupters on the bacterial party line

Nature Chemical Biology volume 1, pages 321–322 (2005)Cite this article

Cross-species quorum sensing in bacteria is mediated by a small molecule autoinducer, AI-2. It has now been demonstrated that AI-2–mediated signaling can be sabotaged by bacteria that degrade AI-2.

This is a preview of subscription content, access via your institution

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

Figure 1: The lsr operon and its regulation.

References

  1. Xavier, K.B. & Bassler, B.L. Nature 437, 750–753 (2005).

    Article  CAS  Google Scholar 

  2. Hastings, J.W. & Nealson, K.H. Annu. Rev. Microbiol. 31, 549–595 (1977).

    Article  CAS  Google Scholar 

  3. Fuqua, C., Parsek, M.R. & Greenberg, E.P. Annu. Rev. Genet. 35, 439–468 (2001).

    Article  CAS  Google Scholar 

  4. Kleerebezem, M., Quadri, L.E., Kuipers, O.P. & de Vos, W.M. Mol. Microbiol. 24, 895–904 (1997).

    Article  CAS  Google Scholar 

  5. Novick, R.P. Mol. Microbiol. 48, 1429–1449 (2003).

    Article  CAS  Google Scholar 

  6. Surette, M.G., Miller, M.B. & Bassler, B.L. Proc. Natl. Acad. Sci. USA 96, 1639–1644 (1999).

    Article  CAS  Google Scholar 

  7. Schauder, S., Shokat, K., Surette, M.G. & Bassler, B.L. Mol. Microbiol. 41, 463–476 (2001).

    Article  CAS  Google Scholar 

  8. Miller, S.T. et al. Mol. Cell 15, 677–687 (2004).

    Article  CAS  Google Scholar 

  9. Taga, M.E., Miller, S.T. & Bassler, B.L. Mol. Microbiol. 50, 1411–1427 (2003).

    Article  CAS  Google Scholar 

  10. Xavier, K.B. & Bassler, B.L. J. Bacteriol. 187, 238–248 (2005).

    Article  CAS  Google Scholar 

  11. Zhu, J. et al. Proc. Natl. Acad. Sci. USA 99, 3129–3134 (2002).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Molecular Pathogenesis Program, Skirball Institute of Biomolecular Medicine, New York University Medical Center, New York, 10016, New York, USA

    Richard P Novick

Authors
  1. Richard P Novick
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Novick, R. Interrupters on the bacterial party line. Nat Chem Biol 1, 321–322 (2005). https://doi.org/10.1038/nchembio1105-321

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/nchembio1105-321

Search

Advanced search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing