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Nature Chemical Biology 1, 71 - 72 (2005)
doi:10.1038/nchembio0705-71

Relaxed specificity in aromatic prenyltransferases

Patrice Koehl1

  1. Patrice Koehl is in the Department of Computer Science and the Genome Center, University of California, Davis, California 95616, USA. e-mail: koehl@cs.ucdavis.edu


Prenylation represents a critical step in the biosynthesis of many natural products. A new study reveals how aromatic prenyltransferase enzymes tolerate diverse aromatic polyketides while still controlling the length of prenyl side chains.

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