Apoptosis occurs through precise cellular pathways, whereas necrosis is generally thought of as a nonspecific cellular response to external damage. However, identification of a chemical inhibitor of necrotic events suggests that specific molecular pathways can also trigger necrosis.
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Nicole Fournier
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Wallach, D. Probing cell death by chemical screening. Nat Chem Biol 1, 68–69 (2005). https://doi.org/10.1038/nchembio0705-68
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DOI: https://doi.org/10.1038/nchembio0705-68
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