Cell division in eukaryotes involves a complex self-organization process that drives the transient assembly of dynamic microtubules into a bipolar spindle around the chromosomes to segregate them to the two daughter cells. Spindle shape and size do not depend on the initial spatial organization of the chromatin, but are determined by microtubule motor activities.
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Vernos, I. Only one spindle, if you please .... Nat Cell Biol 8, 901–902 (2006). https://doi.org/10.1038/ncb0906-901
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DOI: https://doi.org/10.1038/ncb0906-901
