Despite being largely a post-mitotic tissue, adult skeletal muscle exhibits a remarkable capacity for regeneration. A new study has shown that cells derived from mural cells (pericytes) from blood vessels in postnatal human skeletal muscle contribute to robust skeletal muscle regeneration after intra-arterial delivery into a dystrophic mouse model.
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References
Zammit, P. S., Partridge, T. A. & Yablonka-Reuveni, Z. J. Histochem. Cytochem. 54, 1177–1191 (2006).
Collins, C. A. et al. Cell 122, 289–301 (2005).
Charge, S. B. & Rudnicki, M. A. Physiol. Rev. 84, 209–238 (2004).
Asakura, A., Seale, P., Girgis-Gabardo, A. & Rudnicki, M. A. J. Cell Biol. 159, 123–134 (2002).
Peng, H. & Huard, J. Transpl. Immunol. 12, 311–319 (2004).
Torrente, Y. et al. J. Clin. Invest. 114, 182–195 (2004).
Sampaolesi, M. et al. Nature 444, 574–579 (2006).
Dellavalle, A. et al. Nature Cell Biol. 9, 255–267 (2007).
Armulik, A., Abramsson, A. & Betsholtz, C. Circ. Res. 97, 512–523 (2005).
Sims, D. E. Clin. Exp. Pharmacol. Physiol. 27, 842–846 (2000).
Zammit, P. S. et al. J. Cell Biol. 166, 347–357 (2004).
Hall, A. P. Toxicol. Pathol. 34, 763–775 (2006).
Partridge, T. A., Morgan, J. E., Coulton, G. R., Hoffman, E. P. & Kunkel, L. M. Nature 337, 176–179 (1989).
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Morgan, J., Muntoni, F. Mural cells paint a new picture of muscle stem cells. Nat Cell Biol 9, 249–251 (2007). https://doi.org/10.1038/ncb0307-249
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DOI: https://doi.org/10.1038/ncb0307-249
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