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Raising the bar for cancer therapy models

Can mouse cancer models predict the results of phase 3 clinical trials?

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Figure 1: Types of mouse model used to test new cancer therapies.

Katie Vicari

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Acknowledgements

We thank U. Emmenegger as well as members of the Kerbel Lab, in particular C. Hackl, C. Milsom and W. Cruz-Munoz, for their comments and suggestions.

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Correspondence to Giulio Francia or Robert S Kerbel.

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Competing interests

R.S.K. is a member of the scientific advisory board of VisualSonics, Inc., Toronto, which manufactures ultrasound imaging equipment for small animal research.

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Francia, G., Kerbel, R. Raising the bar for cancer therapy models. Nat Biotechnol 28, 561–562 (2010). https://doi.org/10.1038/nbt0610-561

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