1. Robert A. Holt is a senior scientist at the British Columbia Cancer Agency Genome Sciences Centre, Suite 100, 570 West 7th Avenue, Vancouver, British Columbia V5Z 4S6, Canada. e-mail: rholt@bcgsc.ca

Abstract

An entire bacterial genome has been reconstructed by stitching together chemically synthesized DNA fragments, bringing the prospect of an artificial living organism one step closer.

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