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An enriched look at tyrosine phosphorylation

Nature Biotechnology volume 23, pages 36–37 (2005)Cite this article

Immunoaffinity isolation enables the identification of phosphotyrosine peptides on a global level.

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Figure 1: In the study by Rush et al., the proteome is digested into peptides that are then passed through an anti-phosphotyrosine monoclonal antibody column to extract phosphotyrosine (pTyr)-containing peptides.

Bob Crimi

References

  1. Pawson, T. & Scott, J.D. Science 278, 2075–2080 (1997).

    Article  CAS  Google Scholar 

  2. Alonso, A. et al. Cell 117, 699–711 (2004).

    Article  CAS  Google Scholar 

  3. Rush, J. et al. Nat. Biotechnol. 23, 94–101 (2005).

    Article  CAS  Google Scholar 

  4. Ficarro, S.B. et al. Nat. Biotechnol. 20, 301–305 (2002).

    Article  CAS  Google Scholar 

  5. Beausoleil, S.A. et al. Proc. Natl. Acad. Sci. USA 101, 12130–12135 (2004).

    Article  CAS  Google Scholar 

  6. Druker, B.J. et al. N. Engl. J. Med. 344, 1031–1037 (2001).

    Article  CAS  Google Scholar 

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Authors and Affiliations

  1. Laboratory of Proteomics and Analytical Technologies, SAIC-Frederick, Inc., National Cancer Institute at Frederick, P.O. Box B, Frederick, 21702-1201, MD, USA

    Thomas P Conrads & Timothy D Veenstra

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  1. Thomas P Conrads
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  2. Timothy D Veenstra
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Conrads, T., Veenstra, T. An enriched look at tyrosine phosphorylation. Nat Biotechnol 23, 36–37 (2005). https://doi.org/10.1038/nbt0105-36

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