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Cardiac biology

Cell plasticity helps hearts to repair

Fibroblast cells are known as key players in the repair of damaged heart structures. New findings show that injury also induces fibroblasts to become endothelial cells, helping to mend damaged blood vessels. See Article p.585

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Figure 1: Cardiac-cell conversions.

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Correspondence to Raghu Kalluri.

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Miyake, T., Kalluri, R. Cell plasticity helps hearts to repair. Nature 514, 575–576 (2014). https://doi.org/10.1038/nature13928

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