Conferring stem-cell potential on mature cells is not easy. A decisive impediment to this process has now been identified, and its elimination allows almost all mature cells to efficiently adopt a stem-cell identity. See Article p.65
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Notes
*This article and the paper under discussion2 were published online on 18 September 2013.
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Loh, K., Lim, B. Close encounters with full potential. Nature 502, 41–42 (2013). https://doi.org/10.1038/nature12561
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DOI: https://doi.org/10.1038/nature12561