Abstract
Having a baby hospitalized in a neonatal intensive care unit (NICU) is a potentially traumatic event for parents. This article summarizes research documenting heightened symptoms of depression and post-traumatic stress in these parents and reviews studies of the relationship of parental distress with impaired infant and child development. We describe an array of validated screening devices for depression and post-traumatic stress, along with research on risk factors for elevated scores. In making recommendations for screening both mothers and fathers for emotional distress in the NICU, we (a) present commentary on the pros and cons of screening, (b) propose a timetable for screening and (c) describe both supportive interventions for parents in the NICU and a variety of referral possibilities for parents most at risk.
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References
Freda MC, Beck CT, Campbell DC, Dell DL, Ratcliffe S . Quality improvement opportunities in postpartum care In: Berns SD, (ed). Toward Improving the Outcome of Pregnancy III: Enhancing Perinatal Health through Quality, Safety and Performance Initiatives. March of Dimes: White Plains, NY, USA, 2010 pp 88–100.
American College of Obstetricians and Gynecologists, Committee on Obstetric Practice. Committee opinion no. 453: screening for depression during and after pregnancy. Obstet Gynecol 2010; 115 (2 Pt 1): 394–395.
Earls MF The Committee on Psychosocial Aspects of Child and Family Health. Incorporating recognition and management of perinatal and postpartum depression into pediatric practice. Pediatrics 2010; 126 (5): 1032–1039.
American College of Nurse Midwives, Division of Women’s Health Policy and Leadership. Position statement: depression in women 2003 (cited 10 August 2012); The Committee on Psychosocial Aspects of Child and Family Health. Available at www.midwife.org/siteFiles/position/Depression_in_Women_05.pdf.
Bonanno GA, Westphal M, Anthony D, Mancini AD . Resilience to loss and potential trauma. Ann Rev Clin Psychol 2011; 7: 511–535.
Callahan JL, Borja SE, Hynan MT . Modification of the Perinatal PTDS Questionnaire to enhance clinical utility. J Perinatol 2006; 26 (9): 533–539.
DeMier RL, Hynan MT, Harris HB, Manniello RL . Perinatal stressors as predictors of symptoms of posttraumatic stress in mothers of infants at high-risk. J Perinatol 1996; 16 (4): 276–280.
Pierrehumbert B, Nicole A, Muller-Nix C, Forcada-Gue M, Amsermet F . Parental post-traumatic reactions after premature birth: implications for sleeping and eating problems in the infant. Arch Dis Child Fetal Neonatal Ed 2003; 88 (5): F400–F404.
Singer LT, Salvator A, Guo S, Collin M, Lilien L, Baley J . Maternal psychological distress and parenting stress after the birth of a very low-birth-weight infant. JAMA 1999; 281 (9): 799–805.
Vanderbilt D, Bushley T, Young R, Frank DA . Acute posttraumatic stress symptoms among urban mothers with newborns in the neonatal intensive care unit: a preliminary study. J Dev Behav Pediatr 2009; 30 (1): 50–56.
Brandon DH, Tully KP, Silva SG, Malcolm WF, Murtha AP, Turner BS et al. Emotional responses of mothers of late-preterm and term infants. J Obstet Gynecol Neonatal Nurs 2011; 40 (6): 719–731.
Voegtline KM, Stifter CA The Family Life Project Investigators. Late-preterm birth, maternal symptomatology, and infant negativity. Infant Behav Dev 2010; 33 (4): 545–554.
Holditch-Davis D, Bartlett TR, Blickman AL, Miles MS . Posttraumatic stress symptoms in mothers of premature infants. J Obstet Gynecol Neonatal Nurs 2003; 32 (2): 161–171.
Holditch-Davis D, Miles MS, Weaver MA, Black B, Beeber L, Thoyre S et al. Patterns of distress in African-American mothers of preterm infants. J Dev Behav Pediatr 2009; 30 (3): 193–205.
Miles SM, Holditch-Davis D, Schwartz TA, Scher M . Depressive symptoms in mothers of prematurely born infants. J Dev Behav Pediatr 2007; 28 (1): 36–44.
Shaw RJ, Bernard RS, DeBlois R, Ikuta LM, Ginzburg K, Koopman C . The relationship between acute stress disorder and posttraumatic stress disorder in the neonatal intensive care unit. Psychosomatics 2009; 50 (2): 131–137.
Feeley N, Zelkowitz P, Cormier C, Charbonneau L, Lacroix A, Papageorgiou A . Posttraumatic stress among mothers of very low birthweight infants at 6 months after discharge from the neonatal intensive care unit. Appl Nurs Res 2011; 24 (2): 114–117.
Lefkowitz DS, Chiara Baxt C, Evans JR . Prevalence and correlates of posttraumatic stress and postpartum depression in parents of infants in the neonatal intensive care unit (NICU). J Clin Psychol Med Settings 2010; 17 (3): 230–237.
Poehlmann J, Schwichtenberg AJ, Bolt D, Dilworth-Bart J . Predictors of depressive symptom trajectories in mothers of preterm or low birth weight infants. J Fam Psychol 2009; 23 (5): 690–704.
Placencia FX, McCullough LB . Biopsychosocial risks of parental care for high-risk neonates: implications for evidence-based parental counseling. J Perinatol 2012; 32 (5): 381–386.
Mackley AB, Locke RG, Spear ML, Rachel J . Forgotten parent: NICU paternal emotional responses. Adv Neonatal Care 2010; 10 (4): 200–203.
Collaborative Psychiatric Epidemiology Surveys. (updated 2011; cited 22 May 2012) Available from http://www.hcp.med.harvard.edu/ncs/ftpdir/NCS-R_12-month_Prevalence_Estimates.pdf.
O’Hara MW, Swain AM . Rates and risk of postpartum depression—a meta-analysis. Int Rev Psychiatry 1996; 8 (1): 37–54.
Gaynes BN, Gavin N, Meltzer-Brody S, Lohr KN, Swinson T, Gartlehner G et al. Perinatal depression: prevalence, screening accuracy, and screening outcomes. Summary Evidence Report/Technology. Assessment No. 119. Agency for Healthcare Research and Quality: Rockville, MD, USA, 2005 Prepared by the RTI-University of North Carolina Evidence-based Practice Center under Contract No. 290-02-0016.
Paulson JF, Bazemore SD . Prenatal and postpartum depression in fathers and its association to maternal depression. JAMA 2010; 303 (19): 1961–1969.
Paulson JF, Dauber S, Leiferman JA . Individual and combined effects of postpartum depression in mothers and fathers on parenting behavior. Pediatrics 2006; 118 (2): 659–668.
Cox JL, Holden JM, Sagovsky R . Detection of postnatal depression: development of the 10-item Edinburgh Postnatal Depression Scale. Br J Psychiatry 1987; 150 (6): 782–786.
Eberhard-Gran M, Eskild A, Tambs K, Opjordsmoens S, Samuelsen SO . Review of validation studies of the Edinburgh Postnatal Depression Scale. Acta Psychiatr Scand 2001; 104 (4): 243–249.
Radloff LS . The CES-D Scale: a self-report depression scale for research in the general population. Appl Psychol Meas 1977; 1 (3): 358–401.
Beck CT, Gable RK . Postpartum Depression Screening Scale: development and psychometric testing. Nurs Res 2000; 49 (5): 272–282.
Stramrood CAI, Huis In ’T Veld EMJ, Van Pampus MF, Berger LWAR, Vingerhoets AJJM, Weijamr Schultz WCM et al. Measuring posttraumatic stress following childbirth: a critical evaluation of instruments. J Psychosom Obstet Gynaecol 2010; 31 (1): 40–49.
Ayers S, Ford E . Birth trauma: widening our knowledge of postnatal mental health. Eur Health Psychol 2009; 11 (2): 16–19.
Davidson JR, Book SW, Colket JT, Tupler LA, Roth S, David D et al. Assessment of a new self-rating scale for post-traumatic stress disorder. Psychol Med 1997; 27 (1): 153–160.
Weathers F, Ford J . Psychometric properties of the PTSD Checklist (PCL-C, PCL-S, PCL-M, PCL-PR) In Stamm BH, (ed) Measurement of Stress, Trauma, and Adaptation. Sidran Press: Lutherville, MD, USA, 1996 pp 250–251.
Mounts KO . Screening for maternal depression in the neonatal ICU. Clin Perinatol 2009; 36 (1): 137–152.
Diego M, Field T, Jones N, Hernandez-Reif M . Withdrawn and intrusive maternal interaction style and infant frontal EEG symmetry shifts in infants of depressed and non-depressed mothers. Infant Behav Dev 2006; 29 (2): 220–229.
Jones N, Field T, Davalos M . Right frontal EEG asymmetry and lack of empathy in preschool children of depressed mothers. Child Psychiatry Hum Dev 2000; 30 (3): 189–204.
Righetti-Veltema M, Bousquet A, Manzano J . Impact of postpartum depressive symptoms on mother and her 18-month-old infant. Eur Child Adolesc Psychiatry 2003; 12 (2): 75–83.
Murray L, Arteche A, Fearon P, Halligan S, Goodye I, Cooper P . Maternal postnatal depression and the development of depression in offspring up to 16 years of age. J Am Acad Child Adolesc Psychiatry 2011; 50 (5): 460–470.
Ramchandani PG, Psychogiou L, Vlachos H, Iles J, Sethna V, Netsi E et al. Paternal depression: an examination of its links with father, child and family functioning in the postnatal period. Depress Anxiety 2011; 28 (6): 471–477.
Davis RN, Davis MW, Freed GL, Clark SJ . Fathers’ depression related to positive and negative parenting behaviors with 1-year old children. Pediatrics 2011; 127 (4): 612–618.
McManus BM, Poehlmann J . Maternal depression and perceived social support as predictors of cognitive function trajectories during the first 3 years of life for preterm infants in Wisconsin. Child Care Health Dev 2012; 38 (3): 425–434.
Latva R, Korja R, Salmelin RK, Lehtonen L, Tamminen T . How is maternal recollection of the birth experience related to the behavioral and emotional outcome of preterm infants? Early Human Dev 2008; 84 (9): 587–594.
Poehlmann J, Fiese BH . The interaction of maternal and infant vulnerabilities on developing attachment relationships. Dev Psychopathol 2001; 13 (1): 1–11.
Korja R, Savonlahti E, Haataja L, Lapinleimu H, Manninen H, Piha J et alPIPARI Study Group. Attachment representations in mothers of preterm infants. Infant Behav Dev 2009; 32 (3): 305–311.
Keren M, Feldman R, Eidelman AI, Sirota L, Lester B . Clinical interview for high-risk parents of premature infants (CLIP) as a predictor of early disruptions in the mother-infant relationship at the nursery. Infant Mental Health J 2003; 24 (2): 93–110.
Shah PE, Clements M, Poehlmann J . Maternal resolution of grief after preterm birth: implications for infant attachment security. Pediatrics 2011; 127 (2): 284–292.
Seng JS, Low LK, Sperlich M, Ronis DL, Liberzon I . Post-traumatic stress disorder, child abuse history, birthweight and gestational age: a prospective cohort study. BJOG 2011; 118 (11): 1329–1339.
Keim SA, Daniels JL, Dole N, Herring AH, Siega-Riz AM, Scheidt PC . A prospective study of maternal anxiety, perceived stress, and depressive symptoms in relation to infant cognitive development. Early Hum Dev 2011; 87 (5): 373–380.
Muller-Nix C, Forcada-Guex M, Pierrehumbert B, Jaunin L, Borghini A, Ansermet F . Prematurity, maternal stress and mother-child interactions. Early Hum Dev 2004; 79 (2): 145–158.
Forcada-Guex M, Pierrehumbert B, Borghini A, Moessinger A, Muller-Nix C . Early dyadic patterns of mother-infant interactions and outcomes of prematurity at 18 months. Pediatrics 2006; 118 (1): e107–e114.
Orsillo SM . Measures for acute stress disorder and posttraumatic stress disorder In: Antony MM, Orsillo SM, (eds). Practitioner's Guide to Empirically Based Measures of Anxiety. KluwerAcademic/Plenum: New York, NY, USA, 2001 pp 255–307.
Boyd RC, Le HN, Somberg R . Review of screening instruments for postpartum depression. Arch Womens Ment Health 2005; 8 (3): 141–153.
U.S. Preventive Services Task Force. Screening for Depression in Adults: Recommendation Statement. AHRQ Publication No. 10-05143-EF-2, December 2009. Available from http://www.uspreventiveservicestaskforce.org/uspstf09/adultdepression/addeprrs.htm.
Gjerdingen D, Crow S, McGovern P, Miner M, Center B . Postpartum depression screening at well-child visits: validity of a 2-question screen and the PHQ-9. Ann Fam Med 2009; 7 (1): 63–70.
Beeghly M, Weinberg MK, Olson KL, Kernan H, Riley J, Tronick EZ . Stability and change in level of maternal depressive symptomatology during the first postpartum year. J Affect Disord 2002; 71 (1–3): 169–180.
Campbell SB, Cohn JF . Prevalence and correlates of postpartum depression in first-time mothers. J Abnorm Psychol 1991; 100 (4): 594–599.
Beck CT, Gable RK . Comparative analysis of the performance of the Postpartum Depression Screening Scale with two other depression instruments. Nurs Res 2001; 50 (4): 242–250.
Beck CT, Gable RK . Further validation of the Postpartum Depression Screening Scale. Nurs Res 2001; 50 (3): 155–164.
DeRosa N, Logsdon MC . A comparison of screening instruments for depression in postpartum adolescents. J Child Adolesc Psychiatr Nurs 2006; 19 (1): 13–20.
Prins A, Ouimette P, Kimerling R, Cameron RP, Hugelshofer DS, Shaw-Hegwer J et al. The primary care PTSD screen (PC-PTSD): development and operating characteristics. Prim Care Psychiatry 2003; 9 (1): 9–14.
Meyer EC, Zeanah CH, Boukydis CFZ, Lester B . A clinical interview for parents of high-risk infants: concept and applications. Infant Mental Health J 1993; 14 (3): 192–207.
Sampilo M, Lassen S, Belmont J, Parimi P . Development and validation of a psychosocial screening tool to identify high-risk families in the neonatal intensive care unit. The PAT-NICU. Poster presented at the annual conference of the Society of Pediatric Psychology: San Antonio, TX, USA, 2011.
Pai ALH, Patino-Fernandez AM, McSherry M, Beele D, Alderfer MA, Reilly AT et al. The Psychosocial Assessment Tool (PAT): psychometric properties of a screener for psychosocial distress in families of children newly diagnosed with cancer. J Pediatr Psychol 2008; 33 (1): 50–62.
Robertson E, Grace S, Wallington T, Stuart DE . Antenatal risk factors for postpartum depression: a synthesis of recent literature. Gen Hosp Psychiatry 2004; 26 (4): 289–295.
Milgrom J, Gemmill AW, Bilszta JL, Hayes B, Barnett B, Brooks J et al. Antenatal risk factors for postnatal depression: a large prospective study. J Affect Disord 2008; 108 (1-2): 147–157.
Howell EA, Mora P, Leventhal H . Correlates of early postpartum depressive symptoms. Matern Child Health J 2006; 10 (2): 149–157.
Beeghly M, Olson KL, Weinberg MK, Pierre SC, Downey N, Tronik EZ . Prevalence, stability, and sociodemographic correlates of depressive symptoms in black mothers during the first 18 months postpartum. Matern Child Health J 2003; 7 (3): 157–168.
Leonard L . Depression and anxiety disorders during multiple pregnancy and parenthood. J Obstet Gynecol Neonatal Nurs 1998; 27 (3): 329–337.
Thorpe K, Golding J, MacGillivray I, Greenwood R . Comparison of prevalence of depression in mothers of twins and mothers of singletons. BMJ 1991; 302 (6781): 875–878.
Chaudron LH, Szilagyi PG, Campbell AT, Mounts KO, McInerny TK . Legal and ethical considerations: risks and benefits of postpartum depression screening at well-child visits. Pediatrics 2007; 119 (1): 123–128.
Krantz I, Eriksson B, Lundquist-Persson C, Ahlberg BM, Nilstun T . Screening for postpartum depression with the Edinburgh Postnatal Depression Scale (EPDS): an ethical analysis. Scand J Public Health 2008; 36 (2): 211–216.
Buist A, Condon J, Brooks J, Speelman C, Milgrom J, Hayes B et al. Acceptability of routine screening for perinatal depression. J Affect Disord 2006; 93 (1-3): 233–237.
Gemmill AW, Leigh B, Ericksen J, Milgrom J . A survey of the clinical acceptability of screening for postnatal depression in depressed and non-depressed women. BMC Public Health 2006; 6: 211.
Beck CT . Recognizing and screening for postpartum depression in mothers of NICU infants. Adv Neonatal Care 2003; 3 (1): 37–46.
Gooding JS, Cooper LG, Blaine AI, Franck LS, Howse JL, Berns SD . Family support and family-centered care in the neonatal intensive care unit: origins, advances, impact. Seminar Perinatol 2011; 35 (1): 20–28.
The Numbers Count: Mental Disorders in America. National Institute of Mental Health: Rockville, MD, USA (cited 4 June 2010). Available from http://www.nimh.nih.gov/health/publications/the-numbers-count-mental-disorders-in-america/index.shtml.
Nyqvist KH, Anderson GC, Bergman N, Cattaneo A, Charpak N, Davanzo R et al. Toward universal Kangaroo Mother Care: recommendations and report from the First European conference and Seventh International Workshop on Kangaroo Mother Care. Acta Paediatr 2010; 99 (6): 820–826.
Melnyk BM, Feinstein NF, Alpert-Gillis L, Fairbanks E, Crean HF, Sinkin RA et al. Reducing premature infants' length of stay and improving parents' mental health outcomes with the Creating Opportunities for Parent Empowerment (COPE) neonatal intensive care unit program: a randomized, controlled trial. Pediatrics 2006; 118 (5): e1414–e1427.
Als H, Gilkerson L, Duffy FH, Mc Anulty GB, Buehler DM, Vandenberg K et al. A three-center, randomized, controlled trial of individualized developmental care for very low birth weight preterm infants: medical, neurodevelopmental, parenting, and caregiving effects. J Dev Behav Pediatr 2003; 24 (6): 399–408.
Kaaresen PI, Rønning JA, Tunby J, Nordhova SM, Ulvund SE, Dahl LB . A randomized controlled trial of an early-intervention program in low-birth weight children: outcome at 2 years. Early Human Dev 2008; 84 (3): 201–219.
Roman LA, Lindsay JK, Boger RP, DeWys M, Beaumont EJ, Jones AS et al. Parent-to-parent support initiated in the neonatal intensive care unit. Res Nurs Health 1995; 18 (5): 385–394.
Preyde M, Ardal F . Effectiveness of a parent ‘buddy’ program for mothers of very preterm infants in a neonatal intensive care unit. CMAJ 2003; 168 (8): 969–973.
Turan T, Basbakkal Z, Ozbek S . Effect of nursing interventions on stressors of parents of premature infants in neonatal intensive care unit. J Clin Nurs 2008; 17 (21): 2856–2866.
Jotzo M, Poets CF . Helping parents cope with the trauma of premature birth: an evaluation of a trauma-preventive psychological intervention. Pediatrics 2005; 115 (4): 915–919.
Brett J, Staniszewska S, Newburn M, Jones N, Taylor L . A systematic mapping review of effective interventions for communicating with, supporting and providing information to parents of preterm infants. BMJ Open 2011; 1: e000023.
Yawn BP, Dietrich AJ, Wollan P, Bertram S, Graham D, Huff J et al. TRIPPD: A practice based network effectiveness study of postpartum depression and screening. Ann Fam Med 2012; 10 (4): 320–329.
Acknowledgements
We appreciate the feedback of Brian Carter, John Hartline and Lauren Leslie. The recommendations in this article do not indicate an exclusive course of action or serve as a standard of care.
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Hynan, M., Mounts, K. & Vanderbilt, D. Screening parents of high-risk infants for emotional distress: rationale and recommendations. J Perinatol 33, 748–753 (2013). https://doi.org/10.1038/jp.2013.72
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DOI: https://doi.org/10.1038/jp.2013.72
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