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Prevalence of renal anomalies after urinary tract infections in hospitalized infants less than 2 months of age

Journal of Perinatology volume 30, pages 281–285 (2010)Cite this article

Abstract

Objective:

Our aim was to determine the incidence of anatomical abnormalities after a urinary tract infection (UTI) in infants <2 months of age hospitalized in the neonatal intensive care unit (NICU).

Study Design:

This was a retrospective, single-center cohort study of infants <2 months of age in the NICU with a UTI and documented renal imaging.

Result:

We identified 141 infants with UTIs. The mean gestational age and birth weight were 28 weeks and 1254 g, respectively. The most commonly identified pathogen was coagulase-negative Staphylococcus (28%, 44 of 156). A major abnormality was found on at least one imaging study for 4% (5 of 118) of infants. Major abnormalities were noted on 4% (5 of 114) of renal ultrasounds and 2% (2 of 82) of voiding cystourethrography examinations.

Conclusion:

Among infants in the NICU <2 months of age at the time of a UTI, the prevalence of major anatomical abnormalities is <5%.

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Acknowledgements

Dr Benjamin received support from NICHD HD-044799-03. Dr Smith received support from NIH-1K23HD060040-01.

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Authors and Affiliations

  1. Duke University School of Medicine, Durham, NC, USA

    L Nowell

  2. Department of Pediatrics, Duke University Medical Center, Durham, NC, USA

    C Moran, P B Smith, P Seed, C M Cotten, J S Wiener & D K Benjamin Jr

  3. Duke University Clinical Research Institute, Durham, NC, USA

    P B Smith, B D Alexander & D K Benjamin Jr

  4. Department of Medicine and Pathology, Duke University Medical Center, Durham, NC, USA

    B D Alexander

  5. Department of Surgery, Duke University Medical Center, Durham, NC, USA

    J S Wiener

Authors
  1. L Nowell
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  2. C Moran
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  3. P B Smith
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  4. P Seed
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  5. B D Alexander
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  6. C M Cotten
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  7. J S Wiener
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  8. D K Benjamin Jr
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Correspondence to P B Smith.

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Nowell, L., Moran, C., Smith, P. et al. Prevalence of renal anomalies after urinary tract infections in hospitalized infants less than 2 months of age. J Perinatol 30, 281–285 (2010). https://doi.org/10.1038/jp.2009.147

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  • DOI: https://doi.org/10.1038/jp.2009.147

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