Nature Immunology
2, 581 - 582 (2001)
doi:10.1038/89721
B cells with the guts to switchEdward A. Clark1, 2
& Kevin L. Otipoby11
Departments of Immunology and Microbiology, University of Washington, Seattle, WA 98195, USA. 2
eclark@bart.rprc.washington.edu
Expression of mIgM was thought to be essential for the differentiation of B cells expressing antibodies of other classes. New evidence suggests isotype class switching to IgA can occur in the absence of mIgM.
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