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Peeping at the vesicle kiss

Nature Cell Biology volume 1, pages E3–E4 (1999)Cite this article

Abstract

Kiss-and-run fusion, a quick way of coupling exocytotic vesicle fusion to vesicle recycling by endocytosis, can allow full discharge of secretory-vesicle contents, such as neurotransmitters, and is more common than classical endocytosis at high calcium concentrations.

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Figure 1: Two models of coupled exocytosis–endocytosis.

References

  1. Heuser, J. E. & Reese, T. S. J. Cell Biol. 57, 315–344 (1973).

    Article  CAS  Google Scholar 

  2. Ceccarelli, B., Hurlbut, W. P. & Mauro, A. J. Cell Biol. 57, 499– 524 (1973).

    Article  CAS  Google Scholar 

  3. Fesce, R., Grohovaz, F., Valtorta, F. & Meldolesi, J. Trends Cell Biol. 4, 1–4 (1994).

    Article  CAS  Google Scholar 

  4. Neher, E. Nature 363, 497–498 ( 1993).

  5. Alvarez de Toledo, G., Fernandez-Chacon, R. & Fernandez, J. M. Nature 363, 554 –558 (1993).

    Article  CAS  Google Scholar 

  6. Henkel, A. W. & Almers, W. Curr. Opin. Neurobiol. 6, 350–357 (1996).

    Article  CAS  Google Scholar 

  7. Alés, E. et al. Nature Cell Biol. 1, 40– 44 (1999).

    Article  Google Scholar 

  8. Takei, K., Mundigi, O., Daniell, L. & De Camilli, P. J. Cell Biol. 133, 1237–1250 ( 1996).

    Article  CAS  Google Scholar 

  9. Murthy, V. N.. & Stevens, C. F. Nature 392, 497–501 (1998).

    Article  CAS  Google Scholar 

  10. Smith, C. & Neher, E. J. Cell Biol. 139, 885–894 (1997).

    Article  CAS  Google Scholar 

  11. Engisch, K. L. & Nowycky, M. J. Phisiol. (Lond.) 506, 591–608 ( 1998).

    Article  CAS  Google Scholar 

  12. Klingauf, J., Kavalali, E. T. & Tsien, R. W. Nature 394, 581– 585 (1998).

    Article  CAS  Google Scholar 

Download references

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Authors and Affiliations

  1. Department of Neurosciences, DIBIT, San Raffaele Institute, Milano, 20132, Italy

    Riccardo Fesce & Jacopo Meldolesi

  2. CNR Centre of Cytopharmacology and the Department of Pharmacology and Bruno Ceccarelli Centre, University of Milano, Milano, 20129, Italy

    Riccardo Fesce & Jacopo Meldolesi

Authors
  1. Riccardo Fesce
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  2. Jacopo Meldolesi
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Correspondence to Jacopo Meldolesi.

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Fesce, R., Meldolesi, J. Peeping at the vesicle kiss. Nat Cell Biol 1, E3–E4 (1999). https://doi.org/10.1038/8950

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