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Hot on the TRAIL of acute promyelocytic leukemia

Nature Medicine volume 7, pages 662–664 (2001)Cite this article

The ability of all-trans-retinoic acid to stimulate granulocytic differentiation makes it useful in the treatment of acute promyelocytic leukemia. Recent findings suggest that this drug can also induce post-maturation apoptosis through the Apo-2L/TRAIL death ligand (pages 680–686).

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Figure 1: Differentiation-inducing and apoptosis-inducing therapies for APL.

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  1. Leukaemia Research Fund Centre Institute of Cancer Research Chester Beatty Laboratories, London, UK

    Arthur Zelent

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  1. Arthur Zelent
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Zelent, A. Hot on the TRAIL of acute promyelocytic leukemia. Nat Med 7, 662–664 (2001). https://doi.org/10.1038/89031

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