Nature Structural Biology
7, 997 - 999 (2000)
doi:10.1038/81014
How does a bacterium find its middle?Debrabrata RayChaudhuri, G. Scott Gordon
& Andrew Wright
Debrabrata RayChaudhuri, G. Scott Gordon and Andrew Wright
are in the Department of Molecular Biology and Microbiology, Tufts Medical
School, 136 Harrison Avenue, Boston,
Massachusetts 02111, USA.
Correspondence should be addressed to Andrew Wright andrew.wright@tufts.edu or G. Scott Gordon ggordon@opal.tufts.eduEscherichia coli cell division is restricted to the middle
of the cell by the MinCDE system. Through complex interactions with MinC and
MinD, the MinE protein promotes the correct placement of the cell division
apparatus by specifically localizing to the cell center. The first detailed
structural analysis of MinE provides key clues to help understand the critical
actions of this protein.
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