Nature Medicine
6, 129 - 130 (2000)
doi:10.1038/72206
IgG surfaces as an important component in mucosal protectionMarjorie Robert-Guroff
Chief, Section on Immune Biology of Retroviral Infection
Basic Research Laboratory, National Cancer Institute, NIH, Bethesda
, Maryland 20892-5055, USA
guroffm@exchange.nih.gov
New reports showing that passively administered neutralizing IgGs prevent
mucosal HIV transmission in rhesus macaques or macaque neonates support the
inclusion of neutralizing antibodies in vaccine design and suggest clinical
strategies against mother-to-infant transmission (200−210).
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