Linda A. Amos is at the MRC Laboratory of Molecular Biology, Hills Road, Cambridge CB2 2QH, UK.
laa@mrc-lmb.cam.ac.uk
Dimers of the molecular motor kinesin can 'walk' along microtubules. A flexible neck connects the head of one kinesin of the dimer to its partner. When one head is bound to a microtubule, and when this head's neck 'linker' becomes fixed temporarily, pointing towards the next binding site on the microtubule, the partner head is prompted to move forwards.