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focus on cytoskeleton
Nature Cell Biology  2, E15 - E16 (2000)
doi:10.1038/71400

Kinesin sticks its neck out

Linda A. Amos

Linda A. Amos is at the MRC Laboratory of Molecular Biology, Hills Road, Cambridge CB2 2QH, UK.
laa@mrc-lmb.cam.ac.uk

Dimers of the molecular motor kinesin can 'walk' along microtubules. A flexible neck connects the head of one kinesin of the dimer to its partner. When one head is bound to a microtubule, and when this head's neck 'linker' becomes fixed temporarily, pointing towards the next binding site on the microtubule, the partner head is prompted to move forwards.

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Nature Cell Biology
ISSN: 1465-7392
EISSN: 1476-4679
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