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Regenerative medicine

Cell reprogramming gets direct

Nature volume 463, pages 1031–1032 (2010)Cite this article

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In a feat of biological wizardry, one type of differentiated cell has been directly converted into another, completely distinct type. Notably, the approach does not require a stem-cell intermediate stage.

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Figure 1: Indirect and direct routes to cell-lineage reprogramming.

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Authors and Affiliations

  1. Cory R. Nicholas and Arnold R. Kriegstein are at the Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, UCSF School of Medicine, San Francisco, California 94143-0525, USA. kriegsteina@stemcell.ucsf.edu ,

    Cory R. Nicholas & Arnold R. Kriegstein

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  1. Cory R. Nicholas
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  2. Arnold R. Kriegstein
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Nicholas, C., Kriegstein, A. Cell reprogramming gets direct. Nature 463, 1031–1032 (2010). https://doi.org/10.1038/4631031a

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