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Microbiology

Resurrecting a broken genome

A remarkable bacterium can survive extraordinary doses of ionizing radiation that shatter its genome into thousands of pieces. How does it accurately reassemble these DNA fragments into an intact genome?

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Figure 1: DNA repair.

Notes

  1. * This article and the paper concerned3 were published online on 27 September 2006.

References

  1. Battista, J. R., Earl, A. M. & Park, M. J. Trends Microbiol. 7, 362–365 (1999).

    Article  CAS  Google Scholar 

  2. Lange, C. C., Wackett, L. P., Minton, K. W. & Daly, M. J. Nature Biotechnol. 16, 929–933 (1998).

    Article  CAS  Google Scholar 

  3. Zahradka, K. et al. Nature 443, 569–573 (2006).

    Article  ADS  CAS  Google Scholar 

  4. Anderson, A. W., Nordon, H. C., Cain, R. F., Parrish, G. & Duggan, D. Food Technol. 10, 575–578 (1956).

    Google Scholar 

  5. Mattimore, V. & Battista, J. R. J. Bacteriol. 178, 633–637 (1996).

    Article  CAS  Google Scholar 

  6. Chanal, A. et al. Environ. Microbiol. 8, 514–525 (2006).

    Article  CAS  Google Scholar 

  7. Rainey, F. A. et al. Appl. Environ. Microbiol. 71, 5225–5235 (2005).

    Article  CAS  Google Scholar 

  8. Cox, M. M. & Battista, J. R. Nature Rev. Microbiol. 3, 882–892 (2005).

    Article  CAS  Google Scholar 

  9. Makarova, K. S. et al. Microbiol. Mol. Biol. Rev. 65, 44–79 (2001).

    Article  CAS  Google Scholar 

  10. Nassif, N., Penney, J., Pal, S., Engels, W. R. & Gloor, G. B. Mol. Cell. Biol. 14, 1613–1625 (1994).

    Article  CAS  Google Scholar 

  11. Tanaka, M. et al. Genetics 168, 21–33 (2004).

    Article  Google Scholar 

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Lovett, S. Resurrecting a broken genome. Nature 443, 517–519 (2006). https://doi.org/10.1038/443517b

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